Injongo
Injongo yayikukwazisa ngempumelelo nangenyameko iqela elitsha le-anticoagulants (Iimpawu zeNOAC) kuthintelo lwestroke (i-cerebral infarction) kwizigulane ezine-fibrillation ye-atrial (uhlobo lwe-arrhythmia apho intliziyo ibetha ngokungaqhelekanga kwaye idla ngokukhawuleza), ukwenzela ukuba ukungaqiniseki malunga nokhuseleko lokusetyenziswa kwezi zinto kwimisebenzi yemihla ngemihla kunokususwa. Kwakhona bekukho imfuneko yokuphanda ngeendleko-zokusebenza kwezi arhente xa kuthelekiswa nonyango 'lukhoyo' lwe-anticoagulant lwe-fibrillation ye-atrial eNetherlands kusetyenziswa abachasi bevithamin K kunye nokuhlolwa kwe-INR ehambelana nenkonzo ye-thrombosis..
Indlela yokwenza
Ngexesha lokungeniswa kwe-NOACs kuthintelo lwe-stroke kwizigulane ezine-non-valvular atrial fibrillation. (I-NVAF) eNetherlands ekugqibeleni 2012 Ngokwesicelo soMphathiswa wezeMpilo, isikhokelo saqulunqwa kunye neengcebiso malunga nokuqaliswa ngokuthe ngcembe nangokukhuselekileyo kwee-NOACs.. Izizathu eziphambili zale nto yayiyintlangano engcono yokunakekelwa kwe-thrombosis kwilizwe lethu xa kuthelekiswa namanye amazwe aseNtshona kwaye mhlawumbi iindleko eziphezulu zonyango nge-NOAC.. Esi sikhokelo senziwe ngabameli bemibutho yezenzululwazi ebandakanyekayo ngokuthe ngqo (I-NVVC, I-NIV, I-NVN, NOV, I-VAL/NVKC, NVZA/KNMP). Ukubaluleka kokulandela isikhokelo kunye nokuqinisekisa ukuqaliswa ngokucophelela kwagxininiswa yibhodi ye-Dutch Cardiology Association ngelo xesha.. kwakhona, ngokwesicelo sikarhulumente, Ikhomishini yophando iye yasekwa ukuba iqhube uphando oluceliweyo malunga nokhuseleko kunye nokusebenza kakuhle kwezi arhente kwimisebenzi yemihla ngemihla.. Ukuza kuthi ga ngoku, uphononongo olulingwayo lwaqala lwenziwa kunye nesiseko sedatha samabango e-VEKTIS (iinkcukacha ze-inshorensi), apho izigulana zinyangwa nge-anticoagulation yomlomo yesalathiso se-NVAF zachongwa. Ezi datha zikhuselweyo zibonakale zingonelanga (umonde)ziqulathe ulwazi lokukwazi ukuphendula imibuzo ebuziweyo. Uphononongo olutsha lwaye lwayilwa ukuqokelela idatha enxulumene nesigulane kwimisebenzi yemihla ngemihla. isiqingatha sikaFebruwari 2016 sisicwangciso esiqinisekileyo ku-ZonMw 'sobhaliso lwesizwe lwe-anticoagulation ye-NVAF': Dutch AF Registry' kunye nale projekthi ibanzi kulindeleke ukuba iqalise kulo nyaka.
Isiphumo
Ukutenxa kwezinye iintshayelelo, ukuyilwa kwesikhokelo kunye nophando olongezelelweyo kunokuphakanyiswa, ngqo kwimeko Dutch. Ukungaqiniseki kunye nengxoxo eyapheliswa koku yakhokelela kokuninzi (ngokuyinxenye bekungeyomfuneko kwaye akuthetheleleki) upapasho olubi malunga nee-NOAC kunye neengxoxo phakathi kwabasebenzi (oogqirha bentliziyo, abaqeqeshwayo, iingcali zemithambo-luvo, iingcali jikelele kunye nenkonzo thrombosis). Ikhokelele kuphehlelelo olucothayo kunokuba bekulindelwe, apho ingengabo kuphela abavelisi be-NOACs kodwa kunye nemibutho yezigulane engazange yaneliseke: Siphi isigulana ngokwaso kweli bali?
Izifundo
Amaqela amaninzi aye abandakanyeka ekwazisweni kwee-NOACs, ngokuyinxenye nomdla ophikisanayo. Umdla wesigulana uye waphela ngandlel’ ithile ngasemva kule nkalo yoxinzelelo, ngelixa oku bekufanele ukuba kwenze isiseko esiqhubekayo sokungeniswa ngononophelo phantsi koxanduva oludibeneyo lwamaqela ahlukeneyo. Oku kunokwenzeka ukuba kubangele isiphithiphithi esincinci kwaye ngekhe saphendula imibuzo malunga nokhuseleko kunye nokusebenza kakuhle kweendleko ze-NOACs kwakamsinya., ngqo kwimeko Dutch. Hans van Laarhoven (ummeli wombutho wezigulane uHart&Iqela lomphanda) yatsho kamnandi lento: "Oko kuya kuxoxa ngenkqubo yokwazisa uluntu ngokubanzi."
