Inhloso

Ku- 2012 Ngaqala ucwaningo lwePhD olunesihloko esithi: Ukwelashwa kwesengezo sokudla nge-nicotinamide ezinganeni ezinokushoda kokunaka / I-Hyperactivity Disorder. Inhloso yocwaningo bekuwukuthola ukuthi ngabe ukwelashwa nge-nicotinamide (ingxenye ye-vitamin B12) inomphumela wokwelapha ezinganeni ezine-ADHD. Uma kuvela ukuthi ukwelashwa ngesithasiselo esinjalo sokudla kusebenza ekwehliseni izimpawu ze-ADHD, khona-ke lokho bekuyohlangabezana nezifiso zemikhaya eminingi enezingane ezine-ADHD. Lesi sengezo sokudla sibonwe njengenye indlela yokwelapha i-ADHD ngemithi, njenge-methylphenidate. Ububi bemithi ejwayelekile ukuthi ayisebenzi kuzo zonke izingane ezine-ADHD kanye nemiphumela emibi engemihle nayo ingenzeka.. Ngakho-ke inhloso yalolu cwaningo lwe-PhD kwakuwukuthola isisekelo sesayensi sokwelashwa okusha kwe-ADHD okusekelwe esithasiselweni sokudla..

Indlela

Iphrothokholi yocwaningo ilungiswe ngesisekelo sencazelo yesisekelo sethiyori ngokusebenza ngempumelelo kwe-nicotinamide ezinganeni ezine-ADHD.. Le thiyori isuselwe embonweni wokuthi izingane ezine-ADHD azinayo i-amino acid (i-tryptophan) egazini lezingane ezine-ADHD. Kwakusenobufakazi obuncane besayensi balokhu kushoda kwe-tryptophan, ngakho-ke kwanqunywa ukuthi kuqale kuphenywe ukuthi ingabe izingane ezine-ADHD empeleni zinokushoda kwe-tryptophan kaningi kunezingane ezingenayo i-ADHD. Ngakho-ke ukugxila kocwaningo lwe-PhD kushintshele ekuphenyeni ama-amino acid eqenjini elikhulu lezingane ezine-ADHD (n=83) kanye nezingane ezingenayo i-ADHD (n=72).

Umphumela

Ngokuphambene nalokho obekulindelekile, izingane ezine-ADHD azitholakalanga zinengozi eyengeziwe yokuntuleka kwe-tryptophan. Ngamanye amazwi: ukuthethelelwa kokwelashwa kwezingane ezine-ADHD nge-nicotinamide kuphelelwe yisikhathi. Lokhu kuphinde kwabeka okushicilelwe engcupheni.

Nciphisa

Kube ukutholwa okudabukisayo ukuthi imiphumela yocwaningo lwama-amino acid ezinganeni ezine-ADHD yayiwukutholwa okuyize kuphela.. Sithole ukuthi amajenali amaningi esayensi awazimisele ngokuthola lutho futhi ngokuvamile ayenqaba i-athikili ngaphandle kokubuyekezwa. Ngoba besifuna ukuvimbela abanye ososayensi ukuthi baphinde ucwaningo olufanayo, senze konke okusemandleni ethu ukuze sithole incwadi. Ngemva kokwenqatshwa izikhathi ezimbalwa, le ndatshana yanyatheliswa yi-Plos One. Lena ijenali yokufinyelela evulekile, ngakho-ke bangase babe nokwesaba okuncane kokucashunwa okumbalwa okuvela ephepheni elinoziro. Sifundile kulokhu ukuthi ukubekezela kuyaphumelela nokuthi lo mzamo owengeziwe ubaluleke kakhulu. Ngingathanda futhi ukudlulisa lokhu kwabanye ososayensi. Kubalulekile ukuthi isiko lamanje lokushicilela liphulwe nokuthi isayensi ibone ukuthi ngisho nokutholwayo kufanele kwabelwane ngakho futhi kushicilelwe nokuthi lokhu okutholakele kuyigugu futhi kunenjongo njengemiphumela emihle..

Igama: UCarlijn Bergwerff
Inhlangano: Inyuvesi yaseVrije Amsterdam